- What were the Shark Attacks of 1916?, by Nico Medina ; illustrated by Tim Foley
- Ducks overboard!, a true story of plastic in our oceans, Markus Motum
- The price of the ticket, collected nonfiction, 1948-1985, James Baldwin
- Cat, written by Juliet Clutton-Brock
- I am I.M. Pei, Brad Meltzer ; illustrated by Christopher Eliopoulos
- When the sky glows, Nell Cross Beckerman ; illustrated by David Litchfield
- Team trash, a time traveler's guide to sustainability, Kate Wheeler and Trent Huntington
- Duke Ellington's Nutcracker suite, Anna Harwell Celenza ; illustrated by Don Tate
- Mars!, Earthlings welcome, by Mars (with Stacy McAnulty) ; illustrated by Mars (and Stevie Lewis)
- The elements, written by Adrian Dingle
- The secret life of the flying squirrel, Laurence Pringle ; illustrated by Kate Garchinsky
- Emmet to the rescue, by Julia March
- She caught the light, Williamina Stevens Fleming : astronomer, written by Kathryn Lasky ; illustrated by Julianna Swaney
- The secret life of the sea otter, Laurence Pringle ; illustrated by Kate Garchinsky
- Hold on to your music, the inspiring true story of the children of Willesden Lane, by Mona Golabek and Lee Cohen ; adapted by Emil Sher ; illustrated by Sonia Possentini
- I'm a volcano!, by Bridget Heos ; illustrated by Mike Ciccotello
- Ocean!, waves for all, by Ocean (with Stacy McAnulty) ; illustrated by Ocean (and David Litchfield)
- Mr. McCloskey's marvelous mallards, the making of make way for ducklings, Emma Bland Smith ; illustrated by Becca Stadtlander
- Drop, an adventure through the water cycle, Emily Kate Moon
- The green piano, how little me found music, Roberta Flack with Tonya Bolden ; illustrated by Hayden Goodman
- Jack Knight's brave flight, how one gutsy pilot saved the U.S. Air Mail Service, by Jill Esbaum ; illustrated by Stacy Innerst
- An American quilt, unfolding a story of family and slavery, Rachel May
- Ocean, by Emmy Kastner
- Beware the Burmese pythons and other invasive animal species, written by Etta Kaner ; illustrated by Phil Nicholls
- A day in the life of an astronaut, Mars, and the distant stars, written by Mike Barfield ; illustrated by Jess Bradley
- Woman, life, freedom, Marjane Satrapi with Joann Sfar, Mana Neyestani, Pascal Rabaté, Patricia Bolaños, Paco Roca, Shabnam Adiban, Lewis Trondheim, Winshluss, and many more ; translated by Una Dimitrijevic
- Stone soup, morsels of an unsettled life, by Anita Lobel
- The best American science and nature writing 2021, Ed Yong, editor
- Midnight's borders, a people's history of modern India, Suchitra Vijayan
- The cat who lived with Anne Frank, David Lee Miller and Steven Jay Rubin ; illustrated by Elizabeth Baddeley
- The backyard bird chronicles, written and illustrated by Amy Tan
- Grace Banker and her Hello Girls answer the call, the heroic story of WWI telephone operators, written by Claudia Friddell ; illustrated by Elizabeth Baddeley
- The science of baking, by Andrea Beaty and Dr. Theanne Griffith ; illustrations by Steph Stilwell
- Brains on! presents...Earth friend forever, Molly Bloom, Marc Sanchez, and Sanden Totten ; illustrated by Mike Orodán
- Yayoi Kusama covered everything in dots and wasn't sorry, by Fausto Gilberti
- The secret life of the red fox, Laurence Pringle ; illustrated by Kate Garchinsky
- Frogs, a day in the life : what do frogs, toads, and tadpoles get up to all day?, Dr. Itzue W. Caviedes-Solis ; [illustrated by] Henry Rancourt
- Ocean!, waves for all, by Ocean (with Stacy McAnulty) ; illustrated by Ocean (and David Litchfield)
- Game of freedom, Mestre Bimba and the art of Capoeira, Duncan Tonatiuh
- The animal toolkit, how animals use tools, Steve Jenkins & Robin Page
- Our very own dog, Amanda McCardie ; illustrated by Salvatore Rubbino
- Ancestory, Hannah Salyer
- I'm trying to love garbage, words & pictures by Bethany Barton
- Marcel's masterpiece, how a toilet shaped the history of art, Jeff Mack
- Birds of prey, terrifying talons, Joe Flood
- The snow man, Jonah Winter ; illustrated by Jeanette Winter
- Mars!, Earthlings welcome, by Mars ; (with Stacy McAnulty) ; illustrated by Mars (and Stevie Lewis)
- Caterpillars, what will I be when I get to be me?, a TOON book by Kevin McCloskey
- A day in the life of the desert, 6 desert habitats, 108 species, and how to save them, Roxie Munro
- The secret life of viruses, incredible science facts about germs, vaccines, and what you can do to stay healthy, Mariona Tolosa Sisteré, The Ellas Educan Collective